Cryptofolione

Inquiry

For Research Use Only.

Category

Phenols

Cat.No.

NP4695

CAS

160098-78-2

Product Name

Cryptofolione

Structure

Product Details

Description

Cryptofolione is purified from the fruits of Cryptocarya alba. Cryptofolione shows moderate cytotoxicity in both macrophages and T. cruzi amastigotes, and also displays a mild inhibitory effect on the promastigote form of Leishmania spp. Z-Cryptofolione and Cryptomoscatone D2 acts as highly efficacious inhibitors of the G(2) checkpoint, and G(2) checkpoint inhibitors can force cells arrested in G(2) phase by DNA damage to enter mitosis.

Synonyms

(2R)-2-[(1E,4S,6R,7E)-4,6-dihydroxy-8-phenylocta-1,7-dienyl]-2,3-dihydropyran-6-one

Molecular Weight

314.38

Molecular Formula

C19H22O4

Canonical SMILES

C1C=CC(=O)OC1C=CCC(CC(C=CC2=CC=CC=C2)O)O

InChI

InChI=1S/C19H22O4/c20-16(8-4-9-18-10-5-11-19(22)23-18)14-17(21)13-12-15-6-2-1-3-7-15/h1-7,9,11-13,16-18,20-21H,8,10,14H2/b9-4+,13-12+/t16-,17-,18-/m0/s1

InChIKey

JSKFCRSAYKODTM-RURAAYBUSA-N

Appearance

Oil

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