Coumestrol

Inquiry

For Research Use Only.

Category

Coumarins

Cat.No.

NP1071

CAS

479-13-0

Product Name

Coumestrol

Structure

Product Details

Description

Coumestrol is a phytoestrogen found in soybeans, spinach, and clover, mimicking the biological activity of estrogens. Coumestrol binds to the ERα and Erβ to exhibit estrogenic activity. Coumestrol also exhibits weak antagonist activity for pregnane X receptors (IC50 = 12 μM) as well as inverse agonist activity for the constitutive androstane receptors.

Synonyms

Cumoestrol; Cumoesterol; Cumostrol; Coumesterol; 3,9-dihydroxy-[1]benzofuro[3,2-c]chromen-6-one

Molecular Weight

268.224

Molecular Formula

C15H8O5

Canonical SMILES

C1=CC2=C(C=C1O)OC3=C2C(=O)OC4=C3C=CC(=C4)O

InChI

InChI=1S/C15H8O5/c16-7-1-3-9-11(5-7)19-14-10-4-2-8(17)6-12(10)20-15(18)13(9)14/h1-6,16-17H

InChIKey

ZZIALNLLNHEQPJ-UHFFFAOYSA-N