Costunolide

For Research Use Only.
Category
Terpenes
Cat.No.
NP6307
CAS
553-21-9
Product Name
Costunolide
Structure

Product Details

Description
Costunolide, a natural sesquiterpene compound with multiple biological activities; inhibits FPTase with IC50 of 20 μM, also inhibits telomerase with IC50 of 65-90 μM.
Synonyms
CCRIS 6754; NSC 106404; CCRIS6754; NSC106404; CCRIS-6754; NSC-106404;
Molecular Weight
232.32
Molecular Formula
C15H20O2
Canonical SMILES
CC1=CCCC(=CC2C(CC1)C(=C)C(=O)O2)C
InChI
InChI=1S/C15H20O2/c1-10-5-4-6-11(2)9-14-13(8-7-10)12(3)15(16)17-14/h5,9,13-14H,3-4,6-8H2,1-2H3/b10-5+,11-9+/t13-,14+/m0/s1
InChIKey
HRYLQFBHBWLLLL-AHNJNIBGSA-N
Boiling Point
385.4±42.0 °C(Predicted)
Melting Point
106-107 °C
Purity
>98%
Density
1.03±0.1 g/cm3(Predicted)
Solubility
DMSO: soluble10mg/mL (clear solution)
Appearance
Cryst.
Application
Anti-inflammatory and anti-oxidant
Storage
-20°C
Chemical Properties
White crystalline powder, soluble in chloroform, derived from woodsy, Inula magnifica, Kerria japonica, Malachite.
Color
white to beige
Definition
ChEBI: Costunolide is a germacranolide with anthelminthic, antiparasitic and antiviral activities. It has a role as an anthelminthic drug, an antiinfective agent, an antineoplastic agent, an antiparasitic agent, an antiviral drug and a metabolite. It is a germacranolide and a heterobicyclic compound.
Form
powder
Hazard Class
Xi
HS Code
29322090
Risk Statements
36/37/38
Safety Statements
26-24/25
Uses
Costunolide is the oil extracted from Saussurea lappa is used in perfumery and in the Orient for all kinds of diseases.
WGK Germany
3
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