Costunolide

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For Research Use Only.

Size	Price	Stock	Quantity
100 mg	$199	In stock

Category

Terpenes

Cat.No.

NP6307

CAS

553-21-9

Product Name

Costunolide

Structure

Product Details

Description

Costunolide, a natural sesquiterpene compound with multiple biological activities, inhibits FPTase with IC50 of 20 μM, and also inhibits telomerase with IC50 of 65-90 μM.

Synonyms

CCRIS 6754; NSC 106404; CCRIS6754; NSC106404; CCRIS-6754; NSC-106404

Molecular Weight

232.32

Molecular Formula

C15H20O2

Canonical SMILES

CC1=CCCC(=CC2C(CC1)C(=C)C(=O)O2)C

InChI

InChI=1S/C15H20O2/c1-10-5-4-6-11(2)9-14-13(8-7-10)12(3)15(16)17-14/h5,9,13-14H,3-4,6-8H2,1-2H3/b10-5+,11-9+/t13-,14+/m0/s1

InChIKey

HRYLQFBHBWLLLL-AHNJNIBGSA-N

Boiling Point

385.4±42.0 °C(Predicted)

Melting Point

106-107 °C

Purity

>98%

Density

1.03±0.1 g/cm3(Predicted)

Solubility

DMSO: soluble10mg/mL (clear solution)

Appearance

Cryst.

Application

Anti-inflammatory and anti-oxidant

Storage

2 - 8 °C

Chemical Properties

White crystalline powder, soluble in chloroform, derived from woodsy, Inula magnifica, Kerria japonica, Malachite.

Color

white to beige

Definition

ChEBI: Costunolide is a germacranolide with anthelminthic, antiparasitic and antiviral activities. It has a role as an anthelminthic drug, an antiinfective agent, an antineoplastic agent, an antiparasitic agent, an antiviral drug and a metabolite. It is a germacranolide and a heterobicyclic compound.

Form

powder

Hazard Class

HS Code

29322090

Risk Statements

36/37/38

Safety Statements

26-24/25

Uses

Costunolide is the oil extracted from Saussurea lappa is used in perfumery and in the Orient for all kinds of diseases.

WGK Germany

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