Corydalmine

Alkaloids

NP0272

30413-84-4

Corydalmine

Corydalmine,an natural plant alkaloid isolated from roots of Corydalis chaerophylla, can inhibit spore germination of some plant pathogenic as well as saprophytic fungi e.g. Alternaria brassicae, A. brassicicola, A. solani, Curvularia lunata, C. maculans, C. sp., C. pallscens, Erysiphe pisi, Fusarium udum, Helminthosporium species,H. penniseti and a Heterosporium species; it can significantly inhibit spore germination of all the fungi at 100 to 1500 ppm, it is effective against all the fungi at 1500 ppm. C.
l-Corydalmine exhibits activity of potent analgesic in preclinical models, it is under
development as an oral analgesic agent.

(-)-Kikemanine;(13aS)-5,8,13,13a-Tetrahydro-2,3,9-trimethoxy-6H-dibenzo[a,
g]quinolizin-10-ol;Kikemanin;Kikemanine;Schefferine.

(13aS)-2,3,9-trimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-10-ol

341.4

C20H23NO4

COC1=C(C=C2C3CC4=C(CN3CCC2=C1)C(=C(C=C4)O)OC)OC

InChI=1S/C20H23NO4/c1-23-18-9-13-6-7-21-11-15-12(4-5-17(22)20(15)25-3)8-16(21)14(13)10-19(18)24-2/h4-5,9-10,16,22H,6-8,11H2,1-3H3/t16-/m0/s1

DIHXHTWYVOYYDC-INIZCTEOSA-N

501.2±50.0°C (Predicted)

177-178°C

>95%

1.29 g/cm3

Powder

anti-bacterial

Powder

9.97±0.20(Predicted)