Convallatoxin

Inquiry

For Research Use Only.

Category

Steroids

Cat.No.

NP6193

CAS

508-75-8

Product Name

Convallatoxin

Structure

Product Details

Description

Convallatoxin is a cardenolide used in the treatment of congestive heart failure. It may also be used in the treatment of tumor cells at nanomolar concentrations due to its anti-proliferative effects, in particular, human lung cancer. Convallatoxin ameliorates colitic inflammation via activation of PPARγ and suppression of NF-κB.

Synonyms

Corglycone; Convallotoxin; Korglykon; Strophanthidin 3-O-alpha-L-rhamnoside

IUPAC Name

(3S,5S,8R,9S,10S,13R,14S,17R)-5,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde

Molecular Weight

550.64

Molecular Formula

C29H42O10

Canonical SMILES

CC1C(C(C(C(O1)OC2CCC3(C4CCC5(C(CCC5(C4CCC3(C2)O)O)C6=CC(=O)OC6)C)C=O)O)O)O

InChI

InChI=1S/C29H42O10/c1-15-22(32)23(33)24(34)25(38-15)39-17-3-8-27(14-30)19-4-7-26(2)18(16-11-21(31)37-13-16)6-10-29(26,36)20(19)5-9-28(27,35)12-17/h11,14-15,17-20,22-25,32-36H,3-10,12-13H2,1-2H3/t15-,17-,18+,19-,20+,22-,23+,24+,25-,26+,27-,28-,29-/m0/s1

InChIKey

HULMNSIAKWANQO-JQKSAQOKSA-N

Boiling Point

757.3 ℃ at 760 mmHg

Melting Point

235-242 ℃

Purity

95 %

Density

1.41 g/cm³

Solubility

Slightly soluble in water