Description
Communic acid isolated from the branchs of Platycladus orientalis. It exhibits modulatory activity in potentiating antibiotic activity against effluxing strains.
Synonyms
(1S,4aα)-Decahydro-1β-(3-methyl-2,4-pentadienyl)-2-methylene-5,8aβ-dimethylnaphthalene-5β-carboxylic acid;
IUPAC Name
(1S,4aR,5S,8aR)-1,4a-dimethyl-6-methylidene-5-[(2E)-3-methylpenta-2,4-dienyl]-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid
Molecular Formula
C20H30O2
Canonical SMILES
CC(=CCC1C(=C)CCC2C1(CCCC2(C)C(=O)O)C)C=C
InChI
InChI=1S/C20H30O2/c1-6-14(2)8-10-16-15(3)9-11-17-19(16,4)12-7-13-20(17,5)18(21)22/h6,8,16-17H,1,3,7,9-13H2,2,4-5H3,(H,21,22)/b14-8+/t16-,17+,19+,20-/m0/s1
InChIKey
YGBZFOQXPOGACY-VWVSFFKRSA-N
Boiling Point
414.0±34.0 °C(Predicted)
Flash Point
199.8±20.3 °C
Density
1.00±0.1 g/cm3(Predicted)
Application
cytotoxic activity; antimicrobial activity;
Uses
Communic Acid is an extract from the common juniper, Juniperus communis, which is frequently used by indigenous peoples for medicinal purposes and anti-mycobacterial activity.