Description
Cinchonine is isolated from the barks of Cinchona ledgeriana. It has lower toxicity and greater potentiation of in vivo anthracycline activity.
Synonyms
Cinchonan-9-ol, (9S)-; (9S)-Cinchonan-9-ol; (+)-Cinchonine; (8R,9S)-Cinchonine; NSC 6176; d-Cinchonine; (S)-quinolin-4-yl((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanol; Quinidine EP Impurity B
IUPAC Name
(S)-[(1S,2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol
Molecular Formula
C19H22N2O
Canonical SMILES
C=CC1CN2CCC1CC2C(C3=CC=NC4=CC=CC=C34)O
InChI
InChI=1S/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2/t13-,14-,18+,19-/m0/s1
InChIKey
KMPWYEUPVWOPIM-QAMTZSDWSA-N
Boiling Point
464.5±30.0°C at 760 mmHg
Melting Point
244-245°C (dec.)
Solubility
Soluble in DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
Appearance
White to Off-white Solid
Application
antimalarial; antiplatelet effect
Storage
Store at -20°C, protect from light