Chonglou Saponin I

Steroids

NP6126

50773-41-6

Chonglou Saponin I

Chonglou Saponin I, a saponin originally found in a tradition Chinese medicinal herb Paris polyphylla, is a potent apoptosis inducer in drug-resistant HepG2 cells. It has strong anticancer activity and anti-angiogenic effect.

β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-α-L-arabinofuranosyl-(1→4)-O-[6-deoxy-α-L-mannopyranosyl-(1→2)]-; Polyphyllin D; PD; diosgenyl alpha-L-rhamnopyranosyl-(1->2)-(alpha-L-arabinofuranosyl)-(1->4)-beta-D-glucopyranoside; (3β,25R)-Spirost-5-en-3-yl O-α-L-arabinofuranosyl-(1→4)-O-[6-deoxy-α-L-mannopyranosyl-(1→2)]-β-D-glucopyranoside; (+)-Polyphyllin D; 17-Deoxyparis H; Diosgenin 3-O-α-L-arabinofuranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside; Diosgenin 3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-arabinofuranosyl-(1→4)]-β-D-glucopyranoside; Paridis saponin I; Paris I; Paris saponin I; aris saponin Pa; Polyphillin D; Polyphyllin I; Saponin Pa

(2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-5-[(2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)-2-[(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol

855.02

C44H70O16

OCC1OC(OC2C(O)C(OC3OC(C)C(O)C(O)C3O)C(OC4CC5=CCC6C(CCC7(C)C6CC8OC9(OCC(C)CC9)C(C)C87)C5(C)CC4)OC2CO)C(O)C1O

InChI=1S/C44H70O16/c1-19-8-13-44(53-18-19)20(2)30-27(60-44)15-26-24-7-6-22-14-23(9-11-42(22,4)25(24)10-12-43(26,30)5)55-41-38(59-39-35(51)33(49)31(47)21(3)54-39)36(52)37(29(17-46)57-41)58-40-34(50)32(48)28(16-45)56-40/h6,19-21,23-41,45-52H,7-18H2,1-5H3/t19-,20+,21+,23+,24-,25+,26+,27+,28+,29-,30+,31+,32+,33-,34-,35-,36+,37-,38-,39+,40+,41-,42+,43+,44-/m1/s1

LRRDDWMXYOSKIC-IPKCVOQPSA-N

>98%

1.40±0.1 g/cm3

Soluble in DMSO

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anticancer

Store at -20°C

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