Chikusetsu saponin IVa

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For Research Use Only.

Category

Triterpenoids

Cat.No.

NP7042

CAS

51415-02-2

Product Name

Chikusetsu saponin IVa

Structure

Product Details

Description

1. Chikusetsusaponin IVa exerts antithrombotic effects, including minor hemorrhagic events.
2. The signaling of Chikusetsusaponin IVa-induced insulin secretion from βTC3 cells via GPR40 mediated calcium and PKC pathways and thus Chikusetsusaponin IVa might be developed into a new potential for therapeutic agent used in T2DM patients.
3. Chikusetsusaponin IVa is a novel AMPK activator that is capable of bypassing defective insulin signalling and could be useful for the treatment of T2DM or other metabolic disorders.

Synonyms

Chikusetsu saponin IVa

IUPAC Name

(2S,3S,4S,5R,6R)-6-[[(3S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-4,4,6a,6b,11,11,14b-heptamethyl-8a-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycarbonyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid

Molecular Weight

795

Molecular Formula

C42H66O14

Canonical SMILES

CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)OC6C(C(C(C(O6)C(=O)O)O)O)O)C)C)C2C1)C)C(=O)OC7C(C(C(C(O7)CO)O)O)O)C

InChI

1S/C42H66O14/c1-37(2)14-16-42(36(52)56-34-30(48)27(45)26(44)22(19-43)53-34)17-15-40(6)20(21(42)18-37)8-9-24-39(5)12-11-25(38(3,4)23(39)10-13-41(24,40)7)54-35-31(49)28(46)29(47)32(55-35)33(50)51/h8,21-32,34-35,43-49H,9-19H2,1-7H3,(H,50,51)/t21-,22+,23-,24+

InChIKey

YOSRLTNUOCHBEA-SGVKAIFKSA-N

Purity

>98%

Solubility

Soluble in DMSO

Appearance

white powder

Application

antiarrhythmic

Shelf Life

As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly

Storage

Store at -20 °C

Form

Powder

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