Cerevisterol

Inquiry

For Research Use Only.

Category

Steroids

Cat.No.

NP6147

CAS

516-37-0

Product Name

Cerevisterol

Structure

Product Details

Description

Cerevisterol is a natural steroid isolated from the fruit body of Ganoderma lucidum. Cerevisterol can inhibit the activity of DNA polymerase alpha, it is a cytotoxic steroid.
and it can also stimulate NGF-mediated neurite outgrowth on PC12 cells.

Synonyms

Ergosta-7,22-diene-3,5,6-triol; (22E,24R)-24-Methyl-5α-cholesta-7,22-diene-3β,5,6β-triol.

IUPAC Name

(3S,5R,6R,9S,10R,13R,14R,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-1,2,3,4,6,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-3,5,6-triol

Molecular Weight

430.7

Molecular Formula

C28H46O3

Canonical SMILES

CC(C)C(C)C=CC(C)C1CCC2C1(CCC3C2=CC(C4(C3(CCC(C4)O)C)O)O)C

InChI

InChI=1S/C28H46O3/c1-17(2)18(3)7-8-19(4)22-9-10-23-21-15-25(30)28(31)16-20(29)11-14-27(28,6)24(21)12-13-26(22,23)5/h7-8,15,17-20,22-25,29-31H,9-14,16H2,1-6H3/b8-7+/t18-,19+,20-,22+,23-,24-,25+,26+,27+,28-/m0/s1

InChIKey

ARXHRTZAVQOQEU-BRVLHLJYSA-N

Purity

>96%

Density

1.08 g/cm3

Appearance

Powder

Application

inhibit DNA polymerase alpha

Form

Powder