Cephalotaxine

Inquiry

For Research Use Only.

Category

Alkaloids

Cat.No.

NP0522

CAS

24316-19-6

Product Name

Cephalotaxine

Structure

Product Details

Description

Antiviral and antitumor agent.

Synonyms

(-)-Cephalotaxine; ZINC19795976

IUPAC Name

(2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.02,6.06,10.015,19]icosa-1(20),4,13,15(19)-tetraen-3-ol

Molecular Weight

315.36

Molecular Formula

C18H21NO4

Canonical SMILES

COC1=CC23CCCN2CCC4=CC5=C(C=C4C3C1O)OCO5

InChI

InChI=1S/C18H21NO4/c1-21-15-9-18-4-2-5-19(18)6-3-11-7-13-14(23-10-22-13)8-12(11)16(18)17(15)20/h7-9,16-17,20H,2-6,10H2,1H3/t16-,17-,18+/m1/s1

InChIKey

YMNCVRSYJBNGLD-KURKYZTESA-N

Boiling Point

495.2±45.0 °C at 760 mmHg

Flash Point

253.3±28.7 °C

Purity

>98%

Density

1.4±0.1 g/cm3

Solubility

In Vitro:
DMSO : 25 mg/mL(79.27 mM;Need ultrasonic)
In Vivo:
1.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline
Solubility: ≥ 2.5 mg/mL (7.93 mM); Clear solution
2.Add each solvent one by one:10% DMSO >> 90% (20%SBE-β-CDin saline)
Solubility: ≥ 2.5 mg/mL (7.93 mM); Clear solution
3.Add each solvent one by one:10% DMSO >> 90%corn oil
Solubility: ≥ 2.5 mg/mL (7.93 mM); Clear solution

Appearance

Powder

Application

antiviral; antitumor

Storage

Powder:
-20°C: 3 years
4°C: 2 years
In solvent:
-80°C: 6 months
-20°C: 1 month

Color

Yellow

Form

Powder

Vapor Pressure

0.0±1.3 mmHg at 25°C