Carabrone

Sesquiterpenoids

NP5928

1748-81-8

Carabrone

Carabrone, isolated from the herbs of Carpesium abrotanoides, displays cytotoxic, antibacterial and antitumor activity. It also exhibited antifungal activities in vitro and in vivo against Botrytis cinerea, Colletotrichum lagenarium, and Erysiphe graminis.

Octahydro-5a-methyl-3-methylene-5-(3-oxobutyl)-2H-cyclopropa[f]benzofuran-2-one; (3aR,4aα,6aα)-Octahydro-5aα-methyl-3-methylene-5α-(3-oxobutyl)-2H-cyclopropa[f]benzofuran-2-one; (3aR,4aS,5S,5aR,6aR)-5-(3-ketobutyl)-5a-methyl-3-methylene-3a,4,4a,5,6,6a-hexahydrocyclopropa[f]benzofuran-2-one; (3aR,4aS,5S,5aR,6aR)-5a-methyl-3-methylidene-5-(3-oxobutyl)-3a,4,4a,5,6,6a-hexahydrocyclopropa[f][1]benzofuran-2-one; Carabron; Grandicin

248.3

C15H20O3

>98%

Cryst.

Cytotoxic/antibacterial/antitumor

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