Candesartan cilexetil

For Research Use Only.
Category
Impurities
Cat.No.
NP3201
CAS
145040-37-5
Product Name
Candesartan cilexetil
Structure

Product Details

Description
Candesartan blocks the effects of angiotensin II at the angiotensin II type 1 (AT1) receptor. Candesartan cilexetil is a prodrug that is activated to candesartan by ester hydrolysis during gastrointestinal absorption.
Synonyms
TCV-116; TCV 116; TCV116; Candesartan cilexetil
IUPAC Name
1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate
Molecular Weight
610.66
Molecular Formula
C33H34N6O6
Canonical SMILES
CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)OC(C)OC(=O)OC6CCCCC6
InChI
InChI=1S/C33H34N6O6/c1-3-42-32-34-28-15-9-14-27(31(40)43-21(2)44-33(41)45-24-10-5-4-6-11-24)29(28)39(32)20-22-16-18-23(19-17-22)25-12-7-8-13-26(25)30-35-37-38-36-30/h7-9,12-19,21,24H,3-6,10-11,20H2,1-2H3,(H,35,36,37,38)
InChIKey
GHOSNRCGJFBJIB-UHFFFAOYSA-N
Melting Point
161-163°C
Purity
>98%
Appearance
White Solid
Application
Antihypertensive Agents
Form
Powder
Packaging
50 g
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