Cabozantinib

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For Research Use Only.

Size	Price	Stock	Quantity
500 mg	$199	In stock

Category

Impurities

Cat.No.

NP3655

CAS

849217-68-1

Product Name

Cabozantinib

Structure

Product Details

Description

Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.

Molecular Weight

501.51

Molecular Formula

C28H24FN3O5

Canonical SMILES

COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F

InChI

InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34)

InChIKey

ONIQOQHATWINJY-UHFFFAOYSA-N

Purity

>98%

Appearance

White to Light Yellow Powder

Storage

- 20 °C

Packaging

500 mg

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