Bortezomib

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For Research Use Only.

Size	Price	Stock	Quantity
1 g	$398	In stock

Category

Impurities

Cat.No.

NP3656

CAS

179324-69-7

Product Name

Bortezomib

Structure

Product Details

Description

Bortezomib is a potent, reversible and selective 20S proteasome inhibitor with a Ki of 0.6 nM. It is an antineoplastic agent that is used in treatment of refractory multiple myeloma and certain lymphomas.

Synonyms

PS-341; PS 341; PS341; LDP 341; LDP-341; LDP341; MLN341; MLN-341; MLN 341; B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; Velcade; ((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid; N-[(1R)-1-(Dihydroxyboryl)-3-methylbutyl]-Nα-(2-pyrazinylcarbonyl)-L-phenylalaninamide

IUPAC Name

[(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid

Molecular Weight

384.24

Molecular Formula

C19H25BN4O4

Canonical SMILES

B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O

InChI

InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1

InChIKey

GXJABQQUPOEUTA-RDJZCZTQSA-N

Boiling Point

N/A

Melting Point

>122°C

Purity

>98%

Density

1.214±0.1 g/cm3

Solubility

Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

Appearance

White crystalline powder

Storage

Store at -20°C

Packaging

1 g

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