Bonducellin

Inquiry

For Research Use Only.

Category

Flavonoids

Cat.No.

NP2129

CAS

83162-84-9

Product Name

Bonducellin

Structure

Product Details

Description

Bonducellin is isolated from the herbs of Caesalpinia spinosa. Bonducellin shows weak antiproliferative against A2780 human ovarian cancer cell line with the IC50 value of 10.6 uM. Bonducellin has anti-inflammatory activities that can significantly and dose-dependently inhibit the inflammatory mediators: nitric oxide (NO), and cytokines [tumor necrosis factor (TNF)-alpha and interleukin (IL)-12]. Bonducellin shows modulation in the MIC of EtBr by eight fold at a concentration of 62.5 mg/L and also shows significant efflux pump inhibitory activity.

Synonyms

(3E)-7-hydroxy-3-[(4-methoxyphenyl)methylidene]chromen-4-one

IUPAC Name

(3E)-7-hydroxy-3-[(4-methoxyphenyl)methylidene]chromen-4-one

Molecular Weight

282.29

Molecular Formula

C17H14O4

Canonical SMILES

COC1=CC=C(C=C1)C=C2COC3=C(C2=O)C=CC(=C3)O

InChI

InChI=1S/C17H14O4/c1-20-14-5-2-11(3-6-14)8-12-10-21-16-9-13(18)4-7-15(16)17(12)19/h2-9,18H,10H2,1H3/b12-8+