Betulonic acid

Inquiry

For Research Use Only.

Category

Terpenes

Cat.No.

NP6251

CAS

4481-62-3

Product Name

Betulonic acid

Structure

Product Details

Description

Betulonic acid isolated from the branch of Eucalyptus globulus Labill. It could be used as potential leads for the development of new type of anti-cancer agents.

Synonyms

Betulinonic acid;

IUPAC Name

(1R,3aS,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-9-oxo-1-prop-1-en-2-yl-2,3,4,5,6,7,7a,10,11,11b,12,13,13a,13b-tetradecahydro-1H-cyclopenta[a]chrysene-3a-carboxylic acid

Molecular Weight

454.7

Molecular Formula

C30H46O3

Canonical SMILES

CC(=C)C1CCC2(C1C3CCC4C5(CCC(=O)C(C5CCC4(C3(CC2)C)C)(C)C)C)C(=O)O

InChI

InChI=1S/C30H46O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-22,24H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,24+,27-,28+,29+,30-/m0/s1

Boiling Point

548.1±33.0 °C at 760 mmHg

Melting Point

264 °C

Flash Point

299.4±21.9 °C

Purity

97%

Density

1.1±0.1 g/cm3

Solubility

In Vitro:
DMSO : 6.67 mg/mL(14.67 mM;Need ultrasonic)
In Vivo:
1.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline
Solubility: ≥ 0.67 mg/mL (1.47 mM); Clear solution
2.Add each solvent one by one:10% DMSO >> 90%corn oil
Solubility: ≥ 0.67 mg/mL (1.47 mM); Clear solution

Appearance

Powder

Application

antiholestatic effects;

Storage

Powder:
-20°C 3 years
4°C 2 years
In solvent:
-80°C 6 months
-20°C 1 months

Color

White to Off-White

Form

Solid

HS Code

29389090

pKa

4.62±0.70(Predicted)

Safety Statements

24/25

Uses

(+)-Betulonic Acid shows potent cytotoxic activities against PC3, MGC-803, Bcap-37, and MCF-7 cell lines.

Vapor Pressure

0.0±3.2 mmHg at 25°C

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