Description
Betulin can be found in the barks of Betula alba L. Its nanoparticles powder shows an excellent hypoglycemic effect compared with raw Betulin. Betulin alleviated LPS-induced acute lung injury. Besides, Betulin inhibited pro-inflammatory cytokines expression and NF-κB signaling activation through STAT3 signaling. Betulin can also be used in cosmetics material.
Synonyms
Trochol; Betuline; Betulinic Alcohol; Betulinol; Betulol; (1R,3aS,5aR,5bR,9S,11aR,11bR,13aR,13bR)-3a-(Hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-ol
IUPAC Name
(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol
Molecular Formula
C30H50O2
Canonical SMILES
CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)CO
InChI
1S/C28H46O2/c1-18(2)21-10-13-28(17-29)15-14-26(4)22(24(21)28)6-7-23-25(3)11-9-20(30)16-19(25)8-12-27(23,26)5/h19-24,29-30H,1,6-17H2,2-5H3/t19-,20-,21-,22+,23+,24+,25-,26+,27+,28+/m0/s1
InChIKey
XQHSXWXRLYHKSF-VFXNRHIGSA-N
Boiling Point
522.3±23.0 °C at 760 mmHg
Solubility
Soluble in DMSO
Appearance
Pale Brown to Beige Solid
Application
Antineoplastic/anti-HIV
Shelf Life
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.