Avicularin

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For Research Use Only.
Category
Flavonoids
Cat.No.
NP1949
CAS
572-30-5
Product Name
Avicularin
Structure
Structure

Product Details

Description
Avicularin, a natural plant flavonoid isolated from the herbs of Polygonum aviculare, exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. By decreasing C/EBPα-activated GLUT4-mediated glucose uptake in adipocytes and potently inhibiting fatty acid synthase, avicularin can inhibit the accumulation of the intracellular lipids.
Synonyms
Fenicularin; Quercetin 3-alpha-L-arabinofuranoside; Avicularoside
IUPAC Name
3-[(2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
Molecular Weight
434.4
Molecular Formula
C20H18O11
Canonical SMILES
C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(O4)CO)O)O)O)O
InChI
InChI=1S/C20H18O11/c21-6-13-15(26)17(28)20(30-13)31-19-16(27)14-11(25)4-8(22)5-12(14)29-18(19)7-1-2-9(23)10(24)3-7/h1-5,13,15,17,20-26,28H,6H2/t13-,15-,17+,20-/m0/s1
InChIKey
BDCDNTVZSILEOY-UXYNSRGZSA-N
Purity
>98%
Density
1.86 g/cm3
Appearance
Yellow powder
Application
anti-inflammatory
Color
Yellow
Form
Powder
Packaging
10 mg
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