Aucubin

Iridoids

NP3881

479-98-1

Aucubin

Aucubin is an iridoid glycoside with a wide range of biological activities, including anti-inflammatory, anti-microbial, anti-algesic as well as anti-tumor activities. It may be a potential therapeutic choice in the treatment of OA due to its anti-inflammatory and chondroprotective features. Administration of Aucubin improved nerve regeneration in the rat model of sciatic nerve injury, suggesting that Aucubin may be a useful therapeutic compound for the human peripheral nervous system after various nerve injuries. Besides, Aucubin may improve obesity-induced atherosclerosis by attenuating TNF-α-induced inflammatory responses.

(1S,4aR,5S,7aS)-1-4a,5,7a-Tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl b-D-glucopyranoside

(2S,3R,4S,5S,6R)-2-[[(1S,4aR,5S,7aS)-5-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

346.33

C15H22O9

C1=COC(C2C1C(C=C2CO)O)OC3C(C(C(C(O3)CO)O)O)O

InChI=1S/C15H22O9/c16-4-6-3-8(18)7-1-2-22-14(10(6)7)24-15-13(21)12(20)11(19)9(5-17)23-15/h1-3,7-21H,4-5H2/t7-,8+,9+,10+,11+,12-,13+,14-,15-/m0/s1

RJWJHRPNHPHBRN-FKVJWERZSA-N

>98%

Soluble in DMSO

White powder

Anti-inflammatory/chondroprotective

As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly

Store at -20 °C