Description
(-)-Asarinin can be isolated from the herbs of Asarum sieboldii Miq. It possesses the anti- acute cardiac allograft rejection and immunosuppressive activities.
Synonyms
(-)-SESAMINE; ASARININ; EPI-SESAMIN; (-)-5,5'-[(1R,3aα,4S,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis[1,3-benzodioxole]; 5,5'-[(1R,3aα,4S,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(1,3-benzodioxole); L-Asarinin
IUPAC Name
5-[(3R,3aS,4S,6aS)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-1,3-benzodioxole
Molecular Formula
C20H18O6
Canonical SMILES
O1C2=CC=C(C=C2OC1)C3OCC4C(OCC34)C5=CC=C6OCOC6=C5
InChI
InChI=1S/C20H18O6/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19-,20+/m1/s1
InChIKey
PEYUIKBAABKQKQ-FQZPYLGXSA-N
Boiling Point
504.4±50.0 °C at 760 mmHg
Solubility
Chloroform (Slightly), DMSO (Slightly, Sonicated)
Application
Immunosuppressive
Alpha
D20 -118.6°; D23 -122° (chloroform)
Uses
l-Asarinin in combination with pellitorine is a potential larvicides for the control of insecticide-resistant mosquito populations. Possesses antimicrobial activity.