Artesunate

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For Research Use Only.

Size	Price	Stock	Quantity
150 g	$299	In stock

Category

Impurities

Cat.No.

NP2875

CAS

88495-63-0

Product Name

Artesunate

Structure

Product Details

Description

Artesunate is a derivative of the natural product artemisinin which effectively kills the malarial parasites P. falciparum and P. vivax. It also kills trematodes of the species Schistosoma, providing protection against schistosomiasis.

Synonyms

Succinyl dihydroartemisinin; Dihydroartemisinine-12-alpha-succinate; Artesunate (superseded RN); Artesunate; Armax 200; SM-804; WR-256283; HSDB-7458; SM804; WR256283; HSDB7458; SM 804; WR 256283; HSDB 7458

IUPAC Name

4-oxo-4-[[(1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid

Molecular Weight

384.42

Molecular Formula

C19H28O8

Canonical SMILES

CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C

InChI

InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16+,17-,18?,19-/m1/s1

InChIKey

FIHJKUPKCHIPAT-JQXDXKTESA-N

Boiling Point

507.1±50.0 °C at 760 mmHg

Melting Point

131-135 °C

Flash Point

175.6±23.6 °C

Purity

>99%

Density

1.3±0.1 g/cm3

Solubility

Soluble in DMSO (25 mg/ml), and ethanol (25 mg/ml)

Appearance

White Powder

Shelf Life

Artesunate is the sodium salt of the hemisuccinate ester of artemisinin. It is soluble in water but has poor stability in aqueous solutions at neutral or acid pH. In the injectable form, artesunic acid is drawn up in sodium bicarbonate to form sodium artesunate immediately before injection.

Storage

Store at +4 °C, in dark place.

Form

Powder

Packaging

150 g

Vapor Pressure

3.2X10-9 mm Hg at 25 °C (est)

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