Description
Amlexanox is a specific inhibitor of IKKε and TBK1, which inhibits IKKε and TBK1 activity as determined by MBP phosphorylation.
Synonyms
AA-673; AA673; AA 673; CHX 3673; CHX-3673; CHX3673; Amoxanox, Brand name: Aphthasol.
IUPAC Name
2-amino-5-oxo-7-propan-2-ylchromeno[2,3-b]pyridine-3-carboxylic acid
Molecular Formula
C16H14N2O4
Canonical SMILES
CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N
InChI
InChI=1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21)
InChIKey
SGRYPYWGNKJSDL-UHFFFAOYSA-N
Appearance
White to Off-White Solid
Application
Anti-Allergic Agents