Ambroxol hydrochloride

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For Research Use Only.

Category

Impurities

Cat.No.

NP3423

CAS

23828-92-4

Product Name

Ambroxol hydrochloride

Structure

Product Details

Description

AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. It is used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Mucobrox, Mucol, Lasolvan, Mucoangin, Surbronc, Ambolar, and Lysopain.

Synonyms

Ambroxol hydrochloride; NA-872; NA872; NA 872; Abrohexal; Ambril; Ambro-Puren Ambrobeta; Duramucal; Ebromin; Mucosolvan

IUPAC Name

4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexan-1-ol;hydrochloride

Molecular Weight

414.56

Molecular Formula

C13H18Br2N2O.HCl

Canonical SMILES

C1CC(CCC1NCC2=CC(=CC(=C2N)Br)Br)O.Cl

InChI

InChI=1S/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H

InChIKey

QNVKOSLOVOTXKF-UHFFFAOYSA-N

Melting Point

>235 °C

Purity

>98%

Appearance

White Solid

Application

Expectorants

Products

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