Ambroxol hydrochloride

For Research Use Only.
Category
Impurities
Cat.No.
NP3423
CAS
23828-92-4
Product Name
Ambroxol hydrochloride
Structure

Product Details

Description
AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. It is used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Mucobrox, Mucol, Lasolvan, Mucoangin, Surbronc, Ambolar, and Lysopain.
Synonyms
Ambroxol hydrochloride; NA-872; NA872; NA 872; Abrohexal; Ambril; Ambro-Puren Ambrobeta; Duramucal; Ebromin; Mucosolvan
IUPAC Name
4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexan-1-ol;hydrochloride
Molecular Weight
414.56
Molecular Formula
C13H18Br2N2O.HCl
Canonical SMILES
C1CC(CCC1NCC2=CC(=CC(=C2N)Br)Br)O.Cl
InChI
InChI=1S/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H
InChIKey
QNVKOSLOVOTXKF-UHFFFAOYSA-N
Melting Point
>235 °C
Purity
>98%
Appearance
White Solid
Application
Expectorants
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