Alogliptin

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For Research Use Only.

Size	Price	Stock	Quantity
1 g	$298	In stock

Category

Impurities

Cat.No.

NP3015

CAS

850649-61-5

Product Name

Alogliptin

Structure

Product Details

Description

Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibiting greater than 10000-fold selectivity over DPP-8 and DPP-9. Alogliptin is used for the prevention of type 2 diabetes.

Synonyms

(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitril

IUPAC Name

2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]benzonitrile

Molecular Weight

339.39

Molecular Formula

C18H21N5O2

Canonical SMILES

CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCCC(C3)N

InChI

InChI=1S/C18H21N5O2/c1-21-17(24)9-16(22-8-4-7-15(20)12-22)23(18(21)25)11-14-6-3-2-5-13(14)10-19/h2-3,5-6,9,15H,4,7-8,11-12,20H2,1H3/t15-/m1/s1

InChIKey

ZSBOMTDTBDDKMP-OAHLLOKOSA-N

Melting Point

127-129°C

Purity

>98%

Solubility

Sparingly soluble

Appearance

White to Off-White Solid

Application

Hypoglycemic agents

Form

Powder

Packaging

1 g

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