Alismol

For Research Use Only.
Category
Sesquiterpene
Cat.No.
NP5575
CAS
87827-55-2
Product Name
Alismol
Structure

Product Details

Description
Alismol, a sesquiterpenoid isolated from The tubers of Alisma plantago-aquatica Linn, has antihypertensive action. it also can decrease cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for the prevention of anginal attacks.
Alismol inhibits mainly Ca2+ influx through a voltage-dependent Ca2+ channel.
Alismol has inhibitory effect to MMP3 expression and nitric oxide produced in microglial cells.
Synonyms
(1R,3aS,8aS)-1-methyl-4-methylene-7-propan-2-yl-2,3,3a,5,6,8ahexahydroazulen-1-ol; Valerol.
IUPAC Name
(1R,3aS,8aR)-1-methyl-4-methylidene-7-propan-2-yl-2,3,3a,5,6,8a-hexahydroazulen-1-ol
Molecular Weight
220.4
Molecular Formula
C15H24O
Canonical SMILES
CC(C)C1=CC2C(CCC2(C)O)C(=C)CC1
InChI
InChI=1S/C15H24O/c1-10(2)12-6-5-11(3)13-7-8-15(4,16)14(13)9-12/h9-10,13-14,16H,3,5-8H2,1-2,4H3/t13-,14-,15-/m1/s1
InChIKey
BUPJOLXWQXEJSQ-RBSFLKMASA-N
Boiling Point
316.8±21.0 °C(Predicted)
Purity
>98%
Density
0.97±0.1 g/cm3(Predicted)
Appearance
Oil
Application
anti-hypertensive
pKa
14.93±0.40(Predicted)
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