Alantolactone

For Research Use Only.
Category
Sesquiterpenoids
Cat.No.
NP5945
CAS
546-43-0
Product Name
Alantolactone
Structure

Product Details

Description
Alantolactone is a sesquiterpene lactone, which induces activin/Smad3 signaling and disrupts Cripto-1/activin receptor type II A interaction. It exhibits potent antitumor activity.
Synonyms
Helenine; Helenin; Eupatal; (3aR,5S,8aR,9aR)-5,8a-dimethyl-3-methylidene-5,6,7,8,9,9a-hexahydro-3aH-benzo[f][1]benzofuran-2-one
IUPAC Name
(3aR,5S,8aR,9aR)-5,8a-dimethyl-3-methylidene-5,6,7,8,9,9a-hexahydro-3aH-benzo[f][1]benzofuran-2-one
Molecular Weight
232.32
Molecular Formula
C15H20O2
Canonical SMILES
CC1CCCC2(C1=CC3C(C2)OC(=O)C3=C)C
InChI
InChI=1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h7,9,11,13H,2,4-6,8H2,1,3H3/t9-,11+,13+,15+/m0/s1
InChIKey
PXOYOCNNSUAQNS-AGNJHWRGSA-N
Boiling Point
275.0±0.0 °C at 760 mmHg
Purity
>98%
Density
1.1±0.1 g/cm3
Solubility
Soluble in DMSO.
Appearance
White Solid
Application
Anti-inflammatory and antineoplastic
Shelf Life
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Storage
Store at -20 °C
Form
Powder
Packaging
50 mg
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