Akebia saponin D

Triterpenoids

NP7016

39524-08-8

Akebia saponin D

Asperosaponin VI ususlly comes from the root of Dipsacus asperoides C. Y. Cheng et T. M. Ai. Except for its antioxidant activity, treatment of U937 cells with akebia saponin D (ASD) induced apoptosis in a dose dependent manner. ASD exerted strong cytotoxicity against human and murine leukemia cells. ASD may exert apoptosis-inducing activity via induction of apoptosis through activation chiefly via the nitric oxide and apoptosis-related p53 and Bax gene expression.

Akebia saponin D; Hederagenin 3-O-alpha-L-arabinopyranosyl-28-beta-D-glucopyranosyl(1→6)-beta-D-glucopyranoside; Asperosaponin Ⅵ; Akebia saponin D(Asperosaponin VI); Dipsacaceae saponin

[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl] (4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate

929.1

C47H76O18

CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)CO)OC6C(C(C(CO6)O)O)O)C)C)C2C1)C)C(=O)OC7C(C(C(C(O7)COC8C(C(C(C(O8)CO)O)O)O)O)O)O)C

InChI=1S/C47H76O18/c1-42(2)13-15-47(41(59)65-40-37(58)34(55)32(53)26(63-40)20-61-38-36(57)33(54)31(52)25(18-48)62-38)16-14-45(5)22(23(47)17-42)7-8-28-43(3)11-10-29(64-39-35(56)30(51)24(50)19-60-39)44(4,21-49)27(43)9-12-46(28,45)6/h7,23-40,48-58H,8-21H2,1-6H3/t23-,24-,25+,26+,27+,28+,29-,30-,31+,32+,33-,34-,35+,36+,37+,38+,39-,40-,43-,44-,45+,46+,47-/m0/s1

>98%

1.43 g/cm3

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Antioxidant

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