Ailanthone

Inquiry

For Research Use Only.

Category

Diterpenoids

Cat.No.

NP1444

CAS

981-15-7

Product Name

Ailanthone

Structure

Product Details

Description

Ailanthone usually comes from the barks of Ailanthus altissima. A significant pre-emergence herbicide activity was found for most of the extracts which was directly correlated to Ailanthone concentration. Besides, it shows high toxicity.

Synonyms

11β,20-Epoxy-1β,11,12α-trihydroxypicrasa-3,13(21)-diene-2,16-dione; 13,21-Didehydrochaparrinone; Picrasa-3,13(21)-diene-2,16-dione,11,20-epoxy-1,11,12-trihydroxy-, (1b,11b,12a)-

Molecular Weight

376.4

Molecular Formula

C20H24O7

Canonical SMILES

O[C@@H]1C([C@]([C@@]2([C@]3([H])[C@@]1(O)OC2)[C@@](O4)([H])C[C@@]([C@]3(C)[C@@H]5O)([H])C(C)=CC5=O)([H])CC4=O)=C

InChI

1S/C20H24O7/c1-8-4-12(21)16(24)18(3)10(8)5-13-19-7-26-20(25,17(18)19)15(23)9(2)11(19)6-14(22)27-13/h4,10-11,13,15-17,23-25H,2,5-7H2,1,3H3/t10-,11-,13+,15+,16+,17+,18+,19+,20-/m0/s1

InChIKey

WBBVXGHSWZIJST-RLQYZCPESA-N

Boiling Point

641.0±55.0 °C(Predicted)

Melting Point

235-237 °C

Purity

>98%

Density

1.47 g/cm3

Solubility

Soluble in DMSO

Appearance

Powder

Application

Antibacterial/antiprotozoal/anti-tumor

Storage

Sealed in dry,Store in freezer, under -20°C

Color

White

EINECS

683-145-8

Form

Powder

NACRES

NA.77

pKa

11.85±0.70(Predicted)

Uses

Ailanthone has potent antineoplastic activity against anti-hepatocellular carcinoma (HCC) and has been shown to inhibit Huh7 cancer cell growth through cell cycle arrest and apoptosis in vitro and in vivo.

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