Ailanthoidol

Lignans

NP4091

156398-61-7

Ailanthoidol

Ailanthoidol is isolated from the barks of Zanthoxylum ailanthoides. Ailanthoidol possesses potential as a chemopreventive agent against tumor promotion. Ailanthoidol has anti-adipogenic activity that suppresses adipogenesis and it exerts its role mainly through the significant down-regulation of PPARγ and C/EBPα expression. Ailanthoidol has anti-inflammatory activity that inhibits inflammatory reactions by macrophages and protects mice from endotoxin shock.

4-[5-[(E)-3-hydroxyprop-1-enyl]-7-methoxy-1-benzofuran-2-yl]-2-methoxyphenol

4-[5-[(E)-3-hydroxyprop-1-enyl]-7-methoxy-1-benzofuran-2-yl]-2-methoxyphenol

326.34

C19H18O5

COC1=C(C=CC(=C1)C2=CC3=CC(=CC(=C3O2)OC)C=CCO)O

InChI=1S/C19H18O5/c1-22-17-10-13(5-6-15(17)21)16-11-14-8-12(4-3-7-20)9-18(23-2)19(14)24-16/h3-6,8-11,20-21H,7H2,1-2H3/b4-3+

ZDQCRQVGMKIBPN-ONEGZZNKSA-N

97.5%

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