Afzelin

Inquiry

For Research Use Only.

Category

Flavonoids

Cat.No.

NP1852

CAS

482-39-3

Product Name

Afzelin

Structure

Product Details

Description

Afzelin isolated from the herbs of Thesium chinense Turcz. It effectively treats asthma is based on reduction of Th2 cytokine via inhibition of GATA‑binding protein 3 transcription factor, which is the master regulator of Th2 cytokine differentiation and production.

Synonyms

KAEMPFEROL 3-O-GLUCORHAMNOSIDE

IUPAC Name

5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one

Molecular Weight

432.4

Molecular Formula

C21H20O10

Canonical SMILES

CC1C(C(C(C(O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC=C(C=C4)O)O)O)O

InChI

InChI=1S/C21H20O10/c1-8-15(25)17(27)18(28)21(29-8)31-20-16(26)14-12(24)6-11(23)7-13(14)30-19(20)9-2-4-10(22)5-3-9/h2-8,15,17-18,21-25,27-28H,1H3/t8-,15-,17+,18+,21-/m0/s1

InChIKey

SOSLMHZOJATCCP-AEIZVZFYSA-N

Flash Point

272.3°C

Purity

0.98

Density

1.7g/cm3

Appearance

Yellow powder

Application

antibacterial; antimicrobial; promotes cytotoxic effect