Description
It is produced by the strain of Str. albus var. pathocidicus. It is a nitrogen-containing heterocyclic antifungal antibiotic. 8-azaguanine functions as an antimetabolite and easily incorporates into ribonucleic acids, interfering with normal biosynthetic pathways, thus inhibiting cellular growth.
Synonyms
Pathocidin; 5-Amino-1H-vic-triazolo[d]pyrimidin-7-ol; 5-Amino-7-hydroxy-1H-v-triazolo[d]pyrimidine; 5-Amino-3,6-dihydro-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one; 8-AG; Azaguanine; Azan; Guanazol; Guanazolo; NSC 151069; NSC 223526; NSC 749; Pathocidine
IUPAC Name
5-amino-2,6-dihydrotriazolo[4,5-d]pyrimidin-7-one
Molecular Formula
C4H4N6O
Canonical SMILES
C12=NNN=C1N=C(NC2=O)N
InChI
InChI=1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)
InChIKey
LPXQRXLUHJKZIE-UHFFFAOYSA-N
Boiling Point
274.55°C (Predicted)
Solubility
Soluble in Water, Hydrochloric acid, Sodium hydroxide
Appearance
Colorless Acicular Crystal