6-Shogaol

For Research Use Only.
Category
Phenols
Cat.No.
NP5193
CAS
555-66-8
Product Name
6-Shogaol
Structure

Product Details

Description
6-Shogaol is a pungent constituent of ginger similar in chemical structure to gingerol. It has anti-inflammatory properties. lt was reported to have antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. lt effectively inhibit invasion and metastasis of hepatocellular carcinoma through diverse molecular mechanisms, including inhibition of the MAPK and PI3k/Akt pathways and NF-κB and STAT3 activities to suppress expression of MMP-2/-9 and uPA and block angiogenesis. lt inhibits the growth of human cancer cells and induces apoptosis in COLO 205 cells through modulation of mitochondrial functions regulated by reactive oxygen species (ROS).
Synonyms
1-(3-Methoxy-4-hydroxyphenyl)-4-decene-3-one; 1-(4-Hydroxy-3-methoxyphenyl)-4-decen-3-one
IUPAC Name
(E)-1-(4-hydroxy-3-methoxyphenyl)dec-4-en-3-one
Molecular Weight
276.37
Molecular Formula
C17H24O3
Canonical SMILES
CCCCCC=CC(=O)CCC1=CC(=C(C=C1)O)OC
InChI
InChI=1S/C17H24O3/c1-3-4-5-6-7-8-15(18)11-9-14-10-12-16(19)17(13-14)20-2/h7-8,10,12-13,19H,3-6,9,11H2,1-2H3/b8-7+
InChIKey
OQWKEEOHDMUXEO-BQYQJAHWSA-N
Boiling Point
427.5±35.0 °C | Condition: Press: 760 Torr
Purity
>98%
Density
1.0448 g/cm3 | Condition: Temp: 25 °C
Solubility
Chloroform (Slightly), Ethyl Acetate (Slightly)
Appearance
Oil
Application
6-Shogaol exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation. It has a very strong antitussive (anti-cough) effect.
Storage
2-8°C
Form
Oil
Packaging
50 mg / 100 mg
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