6-Shogaol

Phenols

NP5193

555-66-8

6-Shogaol

6-Shogaol is a pungent constituent of ginger similar in chemical structure to gingerol. It has anti-inflammatory properties. lt was reported to have antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. lt effectively inhibit invasion and metastasis of hepatocellular carcinoma through diverse molecular mechanisms, including inhibition of the MAPK and PI3k/Akt pathways and NF-κB and STAT3 activities to suppress expression of MMP-2/-9 and uPA and block angiogenesis. lt inhibits the growth of human cancer cells and induces apoptosis in COLO 205 cells through modulation of mitochondrial functions regulated by reactive oxygen species (ROS).

1-(3-Methoxy-4-hydroxyphenyl)-4-decene-3-one; 1-(4-Hydroxy-3-methoxyphenyl)-4-decen-3-one

(E)-1-(4-hydroxy-3-methoxyphenyl)dec-4-en-3-one

276.37

C17H24O3

CCCCCC=CC(=O)CCC1=CC(=C(C=C1)O)OC

InChI=1S/C17H24O3/c1-3-4-5-6-7-8-15(18)11-9-14-10-12-16(19)17(13-14)20-2/h7-8,10,12-13,19H,3-6,9,11H2,1-2H3/b8-7+

OQWKEEOHDMUXEO-BQYQJAHWSA-N

427.5±35.0 °C | Condition: Press: 760 Torr

>98%

1.0448 g/cm3 | Condition: Temp: 25 °C

Chloroform (Slightly), Ethyl Acetate (Slightly)

Oil

6-Shogaol exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation. It has a very strong antitussive (anti-cough) effect.

2-8ºC

Oil

50 mg / 100 mg