6-Chloroguanine riboside

Inquiry

For Research Use Only.

Category

Impurities

Cat.No.

NP2951

CAS

2004-07-1

Product Name

6-Chloroguanine riboside

Structure

Product Details

Description

6-Chloroguanine riboside is a novel inhibitor of endogenous protein degradation. 6-Chloroguanine riboside is a modified nucleoside with a chlorine atom at the 6-position of the guanine base. It is used in biochemical and pharmacological research to study nucleic acid structure and function, mutagenesis, and potential therapeutic applications, including antiviral and anticancer activities.

Synonyms

6-Chloroguanosine; 2-Amino-6-chloro-9-(β-D-ribofuranosyl)-purine; 6-Chloro-9-β-D-ribofuranosyl-9H-purin-2-amine; 2-Amino-6-chloropurine Ribonucleoside; 2-Amino-6-chloropurine Riboside; NSC 44586; (2R,3R,4S,5R)-2-(2-Amino-6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

IUPAC Name

(2R,3R,4S,5R)-2-(2-amino-6-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Molecular Weight

301.69

Molecular Formula

C10H12ClN5O4

Canonical SMILES

C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(N=C2Cl)N

InChI

InChI=1S/C10H12ClN5O4/c11-7-4-8(15-10(12)14-7)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1

InChIKey

TXWHPSZYRUHEGT-UUOKFMHZSA-N

Boiling Point

729.9±70.0 °C at 760 mmHg

Melting Point

171-172 °C (dec.)

Purity

≥97% by HPLC

Density

2.19 g/cm3

Solubility

Soluble in DMSO, Methanol

Appearance

White Powder

Storage

Store at -20°C

Form

Oil

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