Pinostrobin

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For Research Use Only.

Size	Price	Stock	Quantity
10 mg	$239	In stock

Category

Flavonoids

Cat.No.

NP1825

CAS

480-37-5

Product Name

Pinostrobin

Structure

Product Details

Description

Pinostrobin, which can be extracted from the herbs of Cajanus cajan, may be responsible for the anti-hemorrhagic and analgesic activity (peripheral analgesic activity) of Renealmia alpinia. It leads to depolarisation of the cell potential of endothelial cells. Pinostrobin was able to exert a neuroprotective effect against Aβ(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppressing the mitochondrial pathway of cellular apoptosis. Besides, Pinostrobin (50mg/kg/dose) possesses definite therapeutical effect in the development of lesion score.

Synonyms

Pinostrobin;5-Hydroxy-7-methoxyflavanone;75291-74-6;5-hydroxy-7-methoxy-2-phenylchroman-4-one;480-37-5;(+/-)-Pinostrobin;5-hydroxy-7-methoxy-2-phenyl-2,3-dihydrochromen-4-one;(S)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4-benzopyrone;2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one;()-Pinostrobin;( inverted exclamation markA)-Pinostrobin;CHEMBL210800;SCHEMBL1485747;(2R)-5-hydroxy-7-methoxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one;BCP09997;LMPK12140216;MFCD00017481;AKOS016009493;DB-051500;(+/-)-Pinostrobin, >=99.0% (TLC);NS00074278;

IUPAC Name

5-hydroxy-7-methoxy-2-phenyl-2,3-dihydrochromen-4-one

Molecular Weight

270.28

Molecular Formula

C16H14O4

Canonical SMILES

O=C1C[C@@H](C2=CC=CC=C2)OC3=CC(OC)=CC(O)=C13

InChI

InChI=1S/C16H14O4/c1-19-11-7-12(17)16-13(18)9-14(20-15(16)8-11)10-5-3-2-4-6-10/h2-8,14,17H,9H2,1H3

InChIKey

ORJDDOBAOGKRJV-UHFFFAOYSA-N

Boiling Point

494.9±45.0°C (Predicted)

Melting Point

100°C

Purity

>98%

Density

1.284±0.06 g/cm3(Predicted)

Appearance

Solid

Application

Anti-hemorrhagic/analgesic

Storage

4°C, protect from light
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Color

Yellow

Definition

ChEBI: A monohydroxyflavanone that is (2S)-flavanone substituted by a hydroxy group at position 5 and a methoxy group at position 7 respectively.

EINECS

207-548-1

Form

Powder

Hazard Codes

MDL

MFCD06858342

Packaging

10 mg

pKa

7.40±0.40(Predicted)

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

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