3-Amino-2,6-piperidinedione hydrochloride

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For Research Use Only.

Category

Impurities

Cat.No.

NP3282

CAS

24666-56-6

Product Name

3-Amino-2,6-piperidinedione hydrochloride

Structure

Product Details

Description

3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del(5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation.

Synonyms

3-Amino-2,6-piperidinedione Monohydrochloride; 2-Amino-glutarimide Hydrochloride; 3-Amino-2,6-dioxopiperidine Hydrochloride; 3-Aminopiperidine-2,6-dione Monohydrochloride; DL-Glutamic Acid Imide Hydrochloride; Glutamimide Hydrochloride; 2,6-dioxopiperidine-3-ammonium chloride; Glutamic acid imide hydrochloride; Glutamic acid imide-DL-hydrochloride; ACMC-20a23n; (+-)-3-Amino-2,6-piperidinedione monohydrochloride; AMPD00004; 3-Aminopiperidine-2,6-dione, HCl

IUPAC Name

3-aminopiperidine-2,6-dione;hydrochloride

Molecular Weight

164.59

Molecular Formula

C5H9ClN2O2

Canonical SMILES

C1CC(=O)NC(=O)C1N.Cl

InChI

InChI=1S/C5H8N2O2.ClH/c6-3-1-2-4(8)7-5(3)9;/h3H,1-2,6H2,(H,7,8,9);1H

InChIKey

YCPULGHBTPQLRH-UHFFFAOYSA-N

Boiling Point

334.5 °C at 760 mmHg

Melting Point

> 208 °C (dec.)

Purity

> 99 %

Solubility

Soluble in Water; Slightly soluble in DMSO (Heated); Sparingly soluble in Methanol (Sonicated)

Appearance

White to off-white solid

Storage

2-8 °C

Form

Powder

Packaging

100 mg

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