3,4-Dihydroxybenzoic acid

Phenols

NP5374

99-50-3

3,4-Dihydroxybenzoic acid

3,4-Dihydroxybenzoic acid is discussed to represent antioxidative food components in a human diet rich in fruits and vegetables, and has been shown to prevent carcinogenesis or antitumor growth in vivo, it has apoptotic effect on human gastric carcinoma cells involving JNK/p38 MAPK signaling activation.3,4-Dihydroxybenzoic acid can prevent Abeta (25-35)-induced neuronal cell damage by interfering with the increase of [Ca(2+)](c), and then by inhibiting glutamate release, generation of ROS and caspase-3 activity.3,4-Dihydroxybenzoic acid has protection against Adriamycin cytotoxicity and inhibition of DNA topoisomerase II activity. 3,4-Dihydroxybenzoic acid has nematicidal activity against Meloidogyne incognita.3,4-Dihydroxybenzoic acid shows significant antioxidant using DPPH and antimicrobial activities.

3,4-dihydroxybenzoic acid

3,4-dihydroxybenzoic acid

154.12

C7H6O4

C1=CC(=C(C=C1C(=O)O)O)O

InChI=1S/C7H6O4/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,8-9H,(H,10,11)

YQUVCSBJEUQKSH-UHFFFAOYSA-N

410.7 °C at 760 mmHg

198-202°C

200.00 °F. TCC ( 93.33 °C. )

> 98 %

1.559 g/cm³

Powder

anti-tumor,anti-microbial

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Powder

MFCD00002509

Stable. Incompatible with strong oxidizing agents, strong bases.

0.0000021 [mmHg]