Description
2-Propylpiperidine is a biocompatible polymer that can be used in sublethal doses to induce respiratory paralysis. This compound binds to acetylcholine receptors and blocks the transmission of nerve impulses, leading to temporary paralysis.
Synonyms
2-n-Propylpiperidine; Piperidine, 2-propyl-; Coniine, DL-; (±)-Coniine; dl-Coniine
Canonical SMILES
CCCC1CCCCN1
InChI
InChI=1S/C8H17N/c1-2-5-8-6-3-4-7-9-8/h8-9H,2-7H2,1H3
InChIKey
NDNUANOUGZGEPO-UHFFFAOYSA-N
Boiling Point
56-60°C at 13 Torr
Solubility
Soluble in Diethyl Ether
Appearance
Clear Colorless to Yellow-green Liquid
pKa
pK1:11.24(+1) (25°C,μ=0.5)
Risk Statements
23/24/25-40
Safety Statements
22-36/37/39-45
Toxicity
Piperidine alkaloid obtained
from poison hemlock, Conium maculatum. Alkaline, steam
volatile liquid (b.p. 167C), mousy odor. Darkens and polymerizes
in air. It can be reduced at high temperature with HI
to n-octane and oxidized to pyridine-1-carboxylic acid. The
hydrochloride is used as an antispasmodic.
Uses
Coniine is present in all parts of the plantpoison hemlock (Conium maculatum).