2'-Hydroxy-4,4',6'-trimethoxychalcone

Inquiry

For Research Use Only.

Category

Chalcones

Cat.No.

NP0957

CAS

3420-72-2

Product Name

2'-Hydroxy-4,4',6'-trimethoxychalcone

Structure

Product Details

Description

A chalcone extracted from Kava, which has anticarcinogenic effect. It induces apoptosis in bladder cancer cells via a Bax protein-dependent and mitochondria-dependent apoptotic pathway.

Synonyms

2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-; Chalcone, 2'-hydroxy-4,4',6'-trimethoxy-; 1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one

IUPAC Name

(E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one

Molecular Weight

314.33

Molecular Formula

C18H18O5

Canonical SMILES

O(C)C1=C(C(C=CC2=CC=C(OC)C=C2)=O)C(O)=CC(OC)=C1

InChI

InChI=1S/C18H18O5/c1-21-13-7-4-12(5-8-13)6-9-15(19)18-16(20)10-14(22-2)11-17(18)23-3/h4-11,20H,1-3H3

InChIKey

CGIBCVBDFUTMPT-UHFFFAOYSA-N

Boiling Point

529.9 °C at 760 mmHg

Melting Point

112-116°C(lit.)

Purity

> 95 %

Density

1.207 g/cm³

Solubility

Chloroform (Slightly), Methanol (Slightly)

Appearance

Yellow powder

Application

anti-tumor activity; anti-inflammatory

Storage

2-8°C

Form

Powder

Hazard Codes

MDL

MFCD00017174

pKa

6.78±0.40(Predicted)

Risk Statements

36/37/38

Safety Statements

26-36

Uses

2'-Hydroxy-4,4',6'-trimethoxychalcone may be used to synthesize 2',2"'-dihydroxy-4,4',4'',4"',6',6'''-hexamethoxy[5',5''']bichalcone and 3'-bromo-4,4',6'-trimethoxy-2'-hydroxychalcone.

WGK Germany

Products

Inquiry

* Name:
* Phone:
* Quantity
* Email:
* Service & Products of Interested: [Chalcones] 2'-Hydroxy-4,4',6'-trimethoxychalcone (3420-72-2)
Project Description:
* Verification Code:
SUBMIT