Description
2-Hydroxy-3-methylanthraquinone is a derivative of anthraquinone and is extracted from the herbs of Scutellaria barbata D. Don. It enhances apoptosis of THP-1 cells and U937 cells in part through activation of Fas/FasL, DR4, TRAIL and p-p38MAPK, respectively. It causes caspase-8 and caspase-3 activation mediated apoptotic induction.
Synonyms
2-Hydroxy-3-Methylanthracene-9,10-dione; 2-Methyl-3-hydroxyanthraquinone; 3-Hydroxy-2-methylanthraquinone
Molecular Formula
C15H10O3
Canonical SMILES
CC1=C(C=C2C(=C1)C(=O)C3=CC=CC=C3C2=O)O
InChI
InChI=1S/C15H10O3/c1-8-6-11-12(7-13(8)16)15(18)10-5-3-2-4-9(10)14(11)17/h2-7,16H,1H3
InChIKey
RNJHIYAJJKOFIO-UHFFFAOYSA-N
Boiling Point
439.7±34.0°C (Predicted)
Density
1.371±0.06 g/cm3(Predicted)