2-Flurbiprofen

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For Research Use Only.

Category

Impurities

Cat.No.

NP3244

CAS

51543-40-9

Product Name

2-Flurbiprofen

Structure

Product Details

Description

Flurizan, also called Tarenflurbil, is a nonsteroidal anti-inflammatory drug which inhibits γ-secretase activity leading to preventing the formation of the amyloid β peptide (Aβ42) from amyloid β precursor protein (APP).

Synonyms

(2R)-2-(3-fluoro-4-phenylphenyl)propanoic acid

IUPAC Name

(2R)-2-(3-fluoro-4-phenylphenyl)propanoic acid

Molecular Weight

244.26

Molecular Formula

C15H13FO2

Canonical SMILES

CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O

InChI

InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m1/s1

InChIKey

SYTBZMRGLBWNTM-SNVBAGLBSA-N

Boiling Point

162.4 °C at 760 mmHg

Melting Point

110-113 °C

Purity

> 95 %

Density

1.555 g/cm³

Solubility

Soluble to 49 mM at 25°C in DMSO, to 49 mM at 25°C in ethanol, to <1 mM at 25°C in water, to ~25 mM in DMF, and to ~0.9 mM in PBS (pH 7.2).

Appearance

White solid

Application

(R)-2-Flurbiprofen is the R-isomer of Flurbiprofen (F598700), an anti-inflammatory used as an analgesic.

Storage

Store in a cool and dry place and at 0 - 4 °C for short term (days to weeks) or -31 °C for long term (months to years).

Form

Powder

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