2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol

Inquiry

For Research Use Only.

Category

Impurities

Cat.No.

NP3461

CAS

121660-11-5

Product Name

2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol

Structure

Product Details

Description

2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol is one of Pitavastatin intermediates. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway.

Synonyms

2-Cyclopropyl-4-(4'-fluorophenyl)Quinolyl-3-methanol; Pitavastatin Impurity 31

IUPAC Name

[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methanol

Molecular Weight

293.33

Molecular Formula

C19H16FNO

Canonical SMILES

C1CC1C2=NC3=CC=CC=C3C(=C2CO)C4=CC=C(C=C4)F

InChI

InChI=1S/C19H16FNO/c20-14-9-7-12(8-10-14)18-15-3-1-2-4-17(15)21-19(13-5-6-13)16(18)11-22/h1-4,7-10,13,22H,5-6,11H2

InChIKey

FIZDBNPUFMDGFZ-UHFFFAOYSA-N

Boiling Point

474.7±45.0°C at 760 mmHg

Melting Point

134-136°C

Purity

≥95%

Density

1.286 g/cm³ (Predicted)

Solubility

Soluble in Chloroform (Slightly), Methanol (Slightly)

Appearance

White to pale yellow solid

Application

Pitavastatin intermediate.

Storage

Store at -20°C

Products

Inquiry

* Name:
* Phone:
* Quantity
* Email:
* Service & Products of Interested: [Impurities] 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol (121660-11-5)
Project Description:
* Verification Code:
SUBMIT