2',6'-DIHYDROXY-4'-METHOXYCHALCONE

Inquiry

For Research Use Only.

Category

Chalcones

Cat.No.

NP0955

CAS

18956-15-5

Product Name

2',6'-DIHYDROXY-4'-METHOXYCHALCONE

Structure

Product Details

Description

Pinostrobin chalcone, which can be found in the heartwoods of Lindera umbellata, displayed very remarkable cytotoxic activity against the tested human cancer cells, such as KB, MCF7 and Caski cells (IC50 values of 6.2, 7.3 and 7.7 µg/mL, respectively).

Synonyms

DIHYDROXY-4'-METHOXYCHALCONE, 2',6'-; (E)-1-(2,6-DIHYDROXY-4-METHOXY-PHENYL)-3-PHENYL-PROPENONE; 2',6'-DIHYDROXY-4'-METHOXYCHALCONE; 2-Propen-1-one,1-(2,6-dihy; (E)-1-(2,6-Dihydroxy-4-methoxy-phenyl)-3-phenyl-; (E)-2',6'-Dihydroxy-4'-methoxychalcone; Pistrobin chalcone

IUPAC Name

(E)-1-(2,6-dihydroxy-4-methoxyphenyl)-3-phenylprop-2-en-1-one

Molecular Weight

270.3

Molecular Formula

C16H14O4

Canonical SMILES

COC1=CC(=C(C(=C1)O)C(=O)C=CC2=CC=CC=C2)O

InChI

InChI=1S/C16H14O4/c1-20-12-9-14(18)16(15(19)10-12)13(17)8-7-11-5-3-2-4-6-11/h2-10,18-19H,1H3/b8-7+

Boiling Point

521.1±50.0°C (Predicted)

Melting Point

145°C

Purity

>98%

Density

1.282±0.06 g/cm3(Predicted)

Appearance

Yellow powder

Application

Anti-inflammatory

Storage

2-8°C

EINECS

200-258-5

Form

Powder

MDL

MFCD00017363

pKa

6.70±0.40(Predicted)

Uses

Pinostrobin chalcone is an estrogenic compound from the plant leaves of carya cathayensis sarg.

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