Description
2',3'-Dihydroxy-4'-methoxyacetophenone is a natural phenolic compound found in several plants.
Synonyms
2,3-Dihydroxy-4-methoxyacetohpenone;Dihydroxymethoxyacetohpenonehydrate
IUPAC Name
1-(2,3-dihydroxy-4-methoxyphenyl)ethanone
Molecular Formula
C9H10O4
Canonical SMILES
CC(=O)C1=C(C(=C(C=C1)OC)O)O
InChI
InChI=1S/C9H10O4/c1-5(10)6-3-4-7(13-2)9(12)8(6)11/h3-4,11-12H,1-2H3
InChIKey
VCONERRCKOKCHE-UHFFFAOYSA-N
Boiling Point
359.6±42.0 °C(Predicted)
Storage
Inert atmosphere,Room Temperature
Preparation
Preparation by reaction of acetic acid on pyrogallol 1-methyl ether, with zinc chloride at reflux (155-160°) (Nencki reaction); with boron trifluoride on a steam bath (77%).
Uses
1-(2,3-Dihydroxy-4-methoxyphenyl)ethanone is a a neuroprotective compound isolated from Cynenchum paniculatum. It exerts neuroprotective and cognitive-enhancing activities through its antioxidant activity and may be helpful for the treatment of Alzheimer''s disease.