16-Dehydropregnenolone acetate

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For Research Use Only.

Size	Price	Stock	Quantity
25 g	$299	In stock
100 g	$629	In stock

Category

Steroids

Cat.No.

NP6241

CAS

979-02-2

Product Name

16-Dehydropregnenolone acetate

Structure

Product Details

Description

16-Dehydropregnenolone acetate is an impurity of Abiraterone, which is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga.

Synonyms

Dehydropregnenolone acetate; 16,17-Didehydropregnenolone acetate

IUPAC Name

[(3S,8R,9S,10R,13S,14S)-17-acetyl-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate

Molecular Weight

356.51

Molecular Formula

C23H32O3

Canonical SMILES

CC(=O)C1=CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC(=O)C)C)C

InChI

InChI=1S/C23H32O3/c1-14(24)19-7-8-20-18-6-5-16-13-17(26-15(2)25)9-11-22(16,3)21(18)10-12-23(19,20)4/h5,7,17-18,20-21H,6,8-13H2,1-4H3/t17-,18-,20-,21-,22-,23+/m0/s1

InChIKey

MZWRIOUCMXPLKV-RFOVXIPZSA-N

Boiling Point

464.4±45.0 °C(Predicted)

Melting Point

167-170°C

Purity

> 95%

Density

1.11±0.1 g/cm3(Predicted)

Appearance

White to Off-white Solid

Storage

Store at 2 - 8 °C

Chemical Properties

Off-White Solid

EINECS

213-558-7

Hazard Class

Risk Statements

36/37/38

RTECS

TU4156200

Safety Statements

26-37/39

Uses

16-Dehydropregnenolone Acetate is the dehydration product of Pregnenolone Acetate. 16-Dehydropregnenolone Acetate is used in the preparation of pregnane derivatives and its glycosides as potential anticancer agents.

WGK Germany

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